Depressive symptoms and apathy are associated with psychomotor slowness and frontal activation
نویسندگان
چکیده
منابع مشابه
Poor Dissociation of Patient-Evaluated Apathy and Depressive Symptoms
Apathy has traditionally been conceptualised as part of depression. The appropriateness of this conceptualisation has now been questioned, with the realization that apathy constitutes a distinct neuropsychiatric condition, with separate rehabilitation and patient-care implications to depression. Research on the relationship between apathy and depression has, however, produced mixed results. One...
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Previous data have demonstrated that administration of inflammatory cytokines or their inducers leads to altered basal ganglia function associated with reduced psychomotor speed. Decreased psychomotor speed, referred to clinically as psychomotor retardation, is a cardinal symptom of major depressive disorder (MDD) and has been associated with poor antidepressant treatment response. We therefore...
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BACKGROUND Depressive symptoms of varying severity are prevalent in up to 63% of Alzheimer disease (AD) patients and often result in greater cognitive decline and increased caregiver burden. The current study aimed to determine the neural correlates of depressive symptoms in a sample of AD patients. METHODS Using the Cornell Scale for Depression in Dementia, we assessed 56 patients who met cr...
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ژورنال
عنوان ژورنال: European Archives of Psychiatry and Clinical Neuroscience
سال: 2012
ISSN: 0940-1334,1433-8491
DOI: 10.1007/s00406-012-0296-9